
Have you heard of MPFF or MCP? Modified citrus pectin, otherwise known as the white part, or pith, of citrus fruits is powerful medicine for the heart, lymph, and circulation.
While training in India, I remember drying lemon, orange, and pomegranate peels and then scraping off the pith to make a medicinal white powder. Modern science has now confirmed this ancient Ayurvedic wisdom!
Research has emerged connecting lymphatic circulation to health concerns related to various form of compromised microcirculation, such as cellulite, ankle swelling, poor circulation, cold hands and feet, broken blood vessels, and hemorrhoids.
All of these symptoms have benefited from a patented micronised purified flavonoid fraction (MPFF) derived from the white pith of lemons and oranges, which contains 90% diosmin and 10% hesperidin. This ratio is the same as our LifeSpa formula Lymph Vein HP.
Hemorrhoid Help
This formula is shown in numerous studies to positively affect hemorrhoids, cellulite, blood sugar, venous tone, ankle swelling, lymphatic drainage, and capillary breakage by protecting the body’s lymphatic microcirculation from the ravages of inflammation.1,2,3,4
In two randomized, double-blind, two-month studies, when compared with placebo, 500mg of 90% of micronized diosmin and 10% hesperidin (Lymph Vein HP) twice daily significantly decreased ankle or calf circumference and improved many symptoms of chronic venous insufficiency (CVI) and lymphatic flow.1
Compared with placebo, the duration and/or intensity of individual symptoms of grade 1 or 2 acute internal hemorrhoids improved significantly with three tablets of MPFF 500mg (Lymph Vein HP) twice daily for four days followed by two tablets of MPFF 500mg twice daily for three days.1,2
Two tablets of MPFF 500mg (Lymph Vein HP) daily for 60 or 83 days reduced frequency, duration, and/or severity of acute hemorrhoidal symptoms and improved overall signs and symptoms of chronic (recurrent) hemorrhoids compared with placebo.1,2
Compared with a control group, MPFF significantly reduces risk of secondary bleeding after elective hemorrhoidectomy. In clinical trials, MPFF had a tolerability profile similar to that of placebo.1,2
In an open study on hospital outpatients, pregnant women with hemorrhoids were given therapy with micronized diosmin 90% and hesperidin 10% (Lymph Vein HP) for eight weeks before delivery and four weeks after delivery. 66% had relief from acute hemorrhoidal symptoms by the fourth day, while 53.6% fewer patients had a relapse after delivery. Treatment was well accepted, and did not affect pregnancy, fetal development, birth weight, infant growth, or feeding.
Micronized purified flavonoid fraction (MPFF) with diosmin 90% and hesperidin 10% is safe, acceptable, and effective in treating pregnancy hemorrhoids.1,2,3

Root Out Cellulite
Cellulite is a concern that affects some 80% of women.5 Cutting-edge research suggests cellulite is a consequence of alterations of the lymphatic system that lead to an accumulation of substances in subcutaneous tissue. This can cause accumulation of fluids and other substances in cellular tissue and create cellulite.
In addition to diosmin and hesperidin found in the white pith of certain fruits, another active constituent of citrus pith is called modified citrus pectin (MCP). MCP is rich in certain sugar molecules called galactosides, which bind to and deactivate a group of damaging molecules called galectin-3.6
Galectin-3 molecules are actually helpful to the body, but can causes problems in excess. Under certain conditions, galectin-3 molecules race to sites of tissue damage, and one of their repair mechanisms is to produce scar tissue. However, too much scar tissue can lead to a host of cardiovascular health risks, lymph congestion (cellulite), kidney imbalances, and unhealthy cell division.6
Modified citrus pectin binds to galectin-3 and deactivates it. Imagine the body laying down excess scar tissue in the arteries or lymph in an attempt to heal—cellulite and a variety of other circulation issues can result.
MCP stops galectin-3 from laying down unwanted and potentially harmful scar tissue—so when you eat an orange, be sure to eat the white pith!
Diosmin and hesperidin (Lymph Vein HP) fundamentally help maintain the structure and function of the lymphatic and circulatory system, especially vein strength and competence.7
In pharmacological and clinical studies, MPFF of 90% diosmin and 10% hesperidin from citrus pith promotes normal lymph drainage, healthy capillary permeability, and favorable microcirculation. 8
Microcirculation and lymph congestion can compromise healthy venous drainage in the legs as well as cause build-up of poorly circulated fat in the form of cellulite.
Restoring healthy lymphatic circulation is the first therapy considered in any Ayurvedic evaluation. The study of lymph in Ayurveda is called rasayana, also known as the study of longevity.
So in conclusion: to support healthy lymph circulation (which is connected to such annoyances as hemorrhoids, swollen ankles, cellulite, and varicose veins), eat those pithy white citrus parts or get them super-powered in our Lymph Vein HP.
Naia says
Hey Tommy,
I am not a DR. but have used dehydration and clear, empty veg caps to do this for other substances and it works! Break out the Excalibur, dry the white parts out really well and then when they’re done, chop or blast them in the blender/Vitamix and then put them into the clear veg caps and start out with 1 cap once a day and work up to a level where you feel a difference BUT NEVER GO OVERBOARD and if you’re on MEDS, ask your doctor if it’s OK to try this first. The goal is to find your point of maximum wellness dosage and stick to it. Good luck!
inga says
Is this supplement safe to take turning pregnancy ? I have very swollen ankles !!
chen says
Don’t complicate matters. We actually use the squat stool here at the nursing homes. It helps much better than the prune juice. Demographics in certain countries have also shown that squatting while passing motion will help reduce the incidence of constipation, hemorrhoid and colorectal issues.
Nicole says
Is it possible to pair this with facia blasting or dry brushing?
Michelle says
Please don’t blast your fascia. For muscle pain or tension please look into safer and more effective methods such as Yamuna Body Rolling.
Sumitra Peterson says
I so enjoy your posts. I am a big fan of Ayurveda. My sight is challenged at this time in my life. I used to let my computer read your articles but that is no longer available. I’m guessing you changed it so folks would not copy? I miss it.
Vacheslav says
how about https://www.iblindness.org/?
Craig Schuster says
I second Tommy Kehoe’s interest above as I too do the juicing. Your suggestions would be greatly appreciated. Thank you.
Tommy Kehoe says
I juice a lot of citrus through the week. I would like to learn if it’s possible to make that powder you’re speaking of rather than just throwing out the peels. I have an excalibur dehydrator. Any suggestions?