CoQ10 (Coenzyme Q10) is a naturally-occurring free radical scavenger in the body that supports antioxidant activity in the lymph, blood and cell membranes.
CoQ10 has a major role in energy manufacturing. It helps the body convert carbohydrate metabolites from our food into the main source of energy for most of its cellular processes, ATP (adenosine triphosphate).
Despite the incredibly important benefits of CoQ10, it does have its downfalls in that the body’s natural production decreases with age and that it is not efficiently absorbed by the body with conventional supplementation.
In this article, I’d like to share two ways to boost CoQ10 benefits.
Before CoQ10 it can work its magic, the body needs to convert it into Ubiquinol, the bioactive, reduced, more advanced form of CoQ10.
Ubiquinol, representing over 90% of total body CoQ10, is efficiently converted to the energy-generating ubiquinone form as the body needs it.
It has shown to be a powerful free radical scavenger and protector of the body’s cells and healthy fatty acids from a process called lipid peroxide.
The ubiquinone form of CoQ10 is produced in the mitochondria, where the body manufactures ATP. Here, the ubiquinone is rapidly converted into ubiquinol, the lipid-soluble form that supports antioxidant activity throughout the body.
Conversion of ubiquinone to ubiquinol declines with age, particularly after age 40. Supplementation may help maintain normal levels of ubiquinol in the body as well as address medication-induced nutrient depletion of CoQ10.
In the past, there has been much press suggesting that the ubiquinol form had not been effective as a supplement because it was chemically unstable and easily oxidized.
However, a new process has been developed to stabilize ubiquinol that maintains its structure and stability in the gastrointestinal environment. Learn more about ubiquinol in my online store.
Here are a few stand-out benefits of ubiquinol:
Oxidative stress is detrimental to the integrity and function of cell membranes and tissues, and ultimately, to DNA itself. Ample antioxidant activity must be maintained throughout the body in order to protect vulnerable cells.
Research indicates that ubiquinol supports antioxidant activity, including the regeneration of vitamins C and E, helping to maintain normal levels of free radical activity in the body.
Researchers also suggest a possible role for CoQ10 in the health-promoting control of cell signaling and gene expression. (1)
Antioxidant support from CoQ10 is vital to maintaining the integrity of cholesterol and its role as a precursor to vitamin D, hormones, cell membranes, and brain tissue. Reactive oxygen species, including superoxide released by immune cells, cause the oxidation of cholesterol and can turn a vital biochemical precursor into a toxin. (2)
Research suggests that patients experienced significant support of cardiac function after receiving supplemental ubiquinol (an average 450-580 mg per day). These patients achieved more desirable levels of serum CoQ10 when they switched from ubiquinone to ubiquinol. (3)
Researchers suggest that ubiquinol had dramatically improved absorption. Research on the elderly also appears to indicate that supplemental CoQ10 can increase tolerance to aerobic stress in cardiac tissue. (4)
The role of CoQ10 in aging has become a topic of great interest. Supplementation with both forms of CoQ10—ubiquinone and ubiquinol—was studied in a mouse model. Results suggest that the ubiquinol form more effectively raised CoQ10 levels in the liver (the main target tissue), followed by kidney, heart, and brain. Ubiquinol also appeared to have a more positive effect on maintenance of healthy function of these organs than did ubiquinone.
#2. Shilajit Combined With CoQ10 to Boost Mitochondrial Energy
Research has shown that the nutrient-rich biomass, shilajit, can boost CoQ10 efficiency. Sourced from the Himalayas, shilajit is known for its ability to carry energy and nutrition into the body, particularly at high altitudes.
When CoQ10 and shilajit were combined, scientists found a significant boost in the mitochondria’s ability to convert food into energy.
For thousands of years, shilajit has been used to help support:
- Absorption of vital nutrients
- Enhanced potency and effectiveness of other nutrients
- Sharp intelligence
- Balanced blood sugar
- Efficient detoxification
- Optimal oxygenation and the body’s natural antioxidant response
In one study, CoQ10, which boosts energy in heart, liver and kidney cells, was enhanced by 29% with the addition of shilajit. (9)